Large Language of Life Models

Large Language of Life Models (LLLMs)

About

PreciousGPT is Insilico's lineup of AI models aimed at enabling digital -omics experiments. By training large language models on omics-level data, we have created a new way to run pre-clinical research at minimal costs. Precious models empower scientists to swiftly test their hypotheses using realistic synthesized data.

• Precious1GPT
  Age prediction
  a transformer-based model with aging clock functionality for aging-related pathology research with a simple transformer regressor and transformer classifier architecture.

• Precious2GPT
  Omics profile synthesis
  a compound model combining a transformer and a diffusion architecture with omic data generation capabilities.

• Precious3GPT
  Small molecule emulation
  a genuinely multimodal transformer-based model trained to emulate the workflow of case-control studies, with an emphasis on chemical perturbations. We tokenize multiple data types and train one global model to perform multiple tasks in drug discovery, aging research, and synthetic data generation.

Precious models enable digital compound screening in human and model organism tissues.

We trained our models with data on perturbations induced by 2,500 compounds in hundreds of cell lines.

By combining Precious-3 with Nach01, we can encode and represent any compound with a SMILES-defined structure and make the potential screening library virtually limitless.

Learn more

Visit our website to Access PreciousGPT models and read more about Aging Research, Disease Modelling, Synthetic Data Generation, Drug Discovery, and Other Tasks using our LLLMs.